Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations

Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations

Plain language summary The total number of mutations, or changes, found within the DNA of cancer cells in a tumor sample is known as the tumor mutational burden (TMB). TMB scores have been proposed to be a marker of how well a tumor might respond to immunotherapy, a type of treatment that triggers t...

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Bibliographic Details
Main Authors: Simon Papillon-Cavanagh, Julia F. Hopkins, Shakti H. Ramkissoon, Lee A. Albacker, Alice M. Walsh
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Online Access:https://doaj.org/article/4e897cbc9b7e4b24833e722c9700416e
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