New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity

New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity

In the fight against Malaria, new strategies need to be developed to avoid resistance of the parasite to pharmaceutics and other prevention barriers. Recently, a Host Directed Therapy approach based on the suppression of the starting materials uptake from the host by the parasite has provided excell...

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Bibliographic Details
Main Authors: Francisco José Aguilar-Troyano, Archimede Torretta, Gianluca Rubbini, Alberto Fasiolo, Pilar María Luque-Navarro, María Paz Carrasco-Jimenez, Guiomar Pérez-Moreno, Cristina Bosch-Navarrete, Dolores González-Pacanowska, Emilio Parisini, Luisa Carlota Lopez-Cara
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
antimalarial drug
choline kinase inhibition
Pharmacy and materia medica
RS1-441
Online Access:https://doaj.org/article/4ed42e0cc01e4a2db6f69fca8a4f731c
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https://doaj.org/article/4ed42e0cc01e4a2db6f69fca8a4f731c

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