A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2
Here Zhao et al. report a promising broad-spectrum antiviral alkaline peptide—P9R—that is active against several respiratory, pH-dependent viruses, including Influenza and SARS-CoV-2. P9R interferes with virus internalization by binding to the virus and subsequent inhibition of endosomal acidificati...
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| Lenguaje: | EN |
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Nature Portfolio
2020
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| Acceso en línea: | https://doaj.org/article/4f2f6aa61091410cbf7c4f2708522cde |
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oai:doaj.org-article:4f2f6aa61091410cbf7c4f2708522cde2021-12-02T15:09:25ZA broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-210.1038/s41467-020-17986-92041-1723https://doaj.org/article/4f2f6aa61091410cbf7c4f2708522cde2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17986-9https://doaj.org/toc/2041-1723Here Zhao et al. report a promising broad-spectrum antiviral alkaline peptide—P9R—that is active against several respiratory, pH-dependent viruses, including Influenza and SARS-CoV-2. P9R interferes with virus internalization by binding to the virus and subsequent inhibition of endosomal acidification.Hanjun ZhaoKelvin K. W. ToKong-Hung SzeTimothy Tin-Mong YungMingjie BianHoiyan LamMan Lung YeungCun LiHin ChuKwok-Yung YuenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Hanjun Zhao Kelvin K. W. To Kong-Hung Sze Timothy Tin-Mong Yung Mingjie Bian Hoiyan Lam Man Lung Yeung Cun Li Hin Chu Kwok-Yung Yuen A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| description |
Here Zhao et al. report a promising broad-spectrum antiviral alkaline peptide—P9R—that is active against several respiratory, pH-dependent viruses, including Influenza and SARS-CoV-2. P9R interferes with virus internalization by binding to the virus and subsequent inhibition of endosomal acidification. |
| format |
article |
| author |
Hanjun Zhao Kelvin K. W. To Kong-Hung Sze Timothy Tin-Mong Yung Mingjie Bian Hoiyan Lam Man Lung Yeung Cun Li Hin Chu Kwok-Yung Yuen |
| author_facet |
Hanjun Zhao Kelvin K. W. To Kong-Hung Sze Timothy Tin-Mong Yung Mingjie Bian Hoiyan Lam Man Lung Yeung Cun Li Hin Chu Kwok-Yung Yuen |
| author_sort |
Hanjun Zhao |
| title |
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| title_short |
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| title_full |
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| title_fullStr |
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| title_full_unstemmed |
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 |
| title_sort |
broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and sars-cov-2 |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/4f2f6aa61091410cbf7c4f2708522cde |
| work_keys_str_mv |
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| _version_ |
1718387813605441536 |