Broad and Effective Protection against <named-content content-type="genus-species">Staphylococcus aureus</named-content> Is Elicited by a Multivalent Vaccine Formulated with Novel...

par Jian Deng, Xiaolei Wang, Bao-Zhong Zhang, Peng Gao, Qiubin Lin, Richard Yi-Tsun Kao, Kenth Gustafsson, Kwok-Yung Yuen, Jian-Dong Huang
Publié 2019

Novel Partitivirus Enhances Virulence of and Causes Aberrant Gene Expression in <named-content content-type="genus-species">Talaromyces marneffei</named-content>

par Susanna K. P. Lau, George C. S. Lo, Franklin W. N. Chow, Rachel Y. Y. Fan, James J. Cai, Kwok-Yung Yuen, Patrick C. Y. Woo
Publié 2018

Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai

par Susanna K. P. Lau, Kenneth S. M. Li, Hayes K. H. Luk, Zirong He, Jade L. L. Teng, Kwok-Yung Yuen, Ulrich Wernery, Patrick C. Y. Woo
Publié 2020

A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2

par Hanjun Zhao, Kelvin K. W. To, Kong-Hung Sze, Timothy Tin-Mong Yung, Mingjie Bian, Hoiyan Lam, Man Lung Yeung, Cun Li, Hin Chu, Kwok-Yung Yuen
Publié 2020

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza

par Hanjun Zhao, Kelvin K. W. To, Hin Chu, Qiulu Ding, Xiaoyu Zhao, Cun Li, Huiping Shuai, Shuofeng Yuan, Jie Zhou, Kin-Hang Kok, Shibo Jiang, Kwok-Yung Yuen
Publié 2018

Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein

par Xiaohui Wang, Joy-Yan Lam, Wan-Man Wong, Chun-Kit Yuen, Jian-Piao Cai, Shannon Wing-Ngor Au, Jasper Fuk-Woo Chan, Kelvin K. W. To, Kin-Hang Kok, Kwok-Yung Yuen
Publié 2020

An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells

par Xiaofeng Huang, Min Zheng, Pui Wang, Bobo Wing-Yee Mok, Siwen Liu, Siu-Ying Lau, Pin Chen, Yen-Chin Liu, Honglian Liu, Yixin Chen, Wenjun Song, Kwok-Yung Yuen, Honglin Chen
Publié 2017

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

par Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Can Li, Yanxia Chen, Feifei Liu, Yan Zhao, Hin Chu, Carol Ho-Yan Fong, Pui Wang, Siu-Ying Lau, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen
Publié 2021

Minimal intervention for controlling nosocomial transmission of methicillin-resistant staphylococcus aureus in resource limited setting with high endemicity.

par Vincent Chi-Chung Cheng, Josepha Wai-Ming Tai, Pui-Hing Chau, Jonathan Hon-Kwan Chen, Mei-Kum Yan, Simon Yung-Chun So, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Sally Cheuk-Ying Wong, Pak-Leung Ho, Kwok-Yung Yuen
Publié 2014

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

par Pui Wang, Min Zheng, Siu-Ying Lau, Pin Chen, Bobo Wing-Yee Mok, Siwen Liu, Honglian Liu, Xiaofeng Huang, Conor J. Cremin, Wenjun Song, Yixin Chen, Yik-Chun Wong, Haode Huang, Kelvin Kai-Wong To, Zhiwei Chen, Ningshao Xia, Kwok-Yung Yuen, Honglin Chen
Publié 2019

A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses

par Yufeng Yu, Yong-Qiang Deng, Peng Zou, Qian Wang, Yanyan Dai, Fei Yu, Lanying Du, Na-Na Zhang, Min Tian, Jia-Nan Hao, Yu Meng, Yuan Li, Xiaohui Zhou, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Cheng-Feng Qin, Shibo Jiang, Lu Lu
Publié 2017

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

par Hanjun Zhao, Kelvin K. W. To, Hoiyan Lam, Xinxin Zhou, Jasper Fuk-Woo Chan, Zheng Peng, Andrew C. Y. Lee, Jianpiao Cai, Wan-Mui Chan, Jonathan Daniel Ip, Chris Chung-Sing Chan, Man Lung Yeung, Anna Jinxia Zhang, Allen Wing Ho Chu, Shibo Jiang, Kwok-Yung Yuen
Publié 2021

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

par Pui Wang, Siu-Ying Lau, Shaofeng Deng, Pin Chen, Bobo Wing-Yee Mok, Anna Jinxia Zhang, Andrew Chak-Yiu Lee, Kwok-Hung Chan, Rachel Chun-Yee Tam, Haoran Xu, Runhong Zhou, Wenjun Song, Li Liu, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Zhiwei Chen, Kwok-Yung Yuen, Honglin Chen
Publié 2021

Clonality despite sex: the evolution of host-associated sexual neighborhoods in the pathogenic fungus Penicillium marneffei.

par Daniel A Henk, Revital Shahar-Golan, Khuraijam Ranjana Devi, Kylie J Boyce, Nengyong Zhan, Natalie D Fedorova, William C Nierman, Po-Ren Hsueh, Kwok-Yung Yuen, Tran P M Sieu, Nguyen Van Kinh, Heiman Wertheim, Stephen G Baker, Jeremy N Day, Nongnuch Vanittanakom, Elaine M Bignell, Alex Andrianopoulos, Matthew C Fisher
Publié 2012

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

par Stephan Brouwer, Timothy C. Barnett, Diane Ly, Katherine J. Kasper, David M. P. De Oliveira, Tania Rivera-Hernandez, Amanda J. Cork, Liam McIntyre, Magnus G. Jespersen, Johanna Richter, Benjamin L. Schulz, Gordon Dougan, Victor Nizet, Kwok-Yung Yuen, Yuanhai You, John K. McCormick, Martina L. Sanderson-Smith, Mark R. Davies, Mark J. Walker
Publié 2020

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

par Bobo Wing-Yee Mok, Honglian Liu, Shaofeng Deng, Jiayan Liu, Anna Jinxia Zhang, Siu-Ying Lau, Siwen Liu, Rachel Chun-Yee Tam, Conor J. Cremin, Timothy Ting-Leung Ng, Jake Siu-Lun Leung, Lam-Kwong Lee, Pui Wang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung Chan, Kwok-Yung Yuen, Gilman Kit-Hang Siu, Honglin Chen
Publié 2021

Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection

par Xiaohui Wang, Xiang Lin, Zihan Zheng, Bingtai Lu, Jun Wang, Andy Hee-Meng Tan, Meng Zhao, Jia Tong Loh, Sze Wai Ng, Qian Chen, Fan Xiao, Enyu Huang, King-Hung Ko, Zhong Huang, Jingyi Li, Kin-Hang Kok, Gen Lu, Xiaohui Liu, Kong-Peng Lam, Wanli Liu, Yuxia Zhang, Kwok-Yung Yuen, Tak Wah Mak, Liwei Lu
Publié 2021

Isolation of MERS-related coronavirus from lesser bamboo bats that uses DPP4 and infects human-DPP4-transgenic mice

par Susanna K. P. Lau, Rachel Y. Y. Fan, Longchao Zhu, Kenneth S. M. Li, Antonio C. P. Wong, Hayes K. H. Luk, Emily Y. M. Wong, Carol S. F. Lam, George C. S. Lo, Joshua Fung, Zirong He, Felix C. H. Fok, Rex K. H. Au-Yeung, Libiao Zhang, Kin-Hang Kok, Kwok-Yung Yuen, Patrick C. Y. Woo
Publié 2021

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

par Qi Zhang, Bin Ju, Jiwan Ge, Jasper Fuk-Woo Chan, Lin Cheng, Ruoke Wang, Weijin Huang, Mengqi Fang, Peng Chen, Bing Zhou, Shuo Song, Sisi Shan, Baohua Yan, Senyan Zhang, Xiangyang Ge, Jiazhen Yu, Juanjuan Zhao, Haiyan Wang, Li Liu, Qining Lv, Lili Fu, Xuanling Shi, Kwok Yung Yuen, Lei Liu, Youchun Wang, Zhiwei Chen, Linqi Zhang, Xinquan Wang, Zheng Zhang
Publié 2021

ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury

par Tomokazu Yamaguchi, Midori Hoshizaki, Takafumi Minato, Satoru Nirasawa, Masamitsu N. Asaka, Mayumi Niiyama, Masaki Imai, Akihiko Uda, Jasper Fuk-Woo Chan, Saori Takahashi, Jianbo An, Akari Saku, Ryota Nukiwa, Daichi Utsumi, Maki Kiso, Atsuhiro Yasuhara, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Yuji Fujino, Satoru Motoyama, Satoshi Nagata, Josef M. Penninger, Haruhiko Kamada, Kwok-Yung Yuen, Wataru Kamitani, Ken Maeda, Yoshihiro Kawaoka, Yasuhiro Yasutomi, Yumiko Imai, Keiji Kuba
Publié 2021