The key role of genomics in modern vaccine and drug design for emerging infectious diseases.

par Kate L Seib, Gordon Dougan, Rino Rappuoli
Publié 2009

High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale

par Sushmita Sridhar, Sally Forrest, Ben Warne, Mailis Maes, Stephen Baker, Gordon Dougan, Josefin Bartholdson Scott
Publié 2021

Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium

par Sushmita Sridhar, Sally Forrest, Derek Pickard, Claire Cormie, Emily A. Lees, Nicholas R. Thomson, Gordon Dougan, Stephen Baker
Publié 2021

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.

par Ellen S C Bushell, Andrea Ecker, Timm Schlegelmilch, David Goulding, Gordon Dougan, Robert E Sinden, George K Christophides, Fotis C Kafatos, Dina Vlachou
Publié 2009

The architecture and stabilisation of flagellotropic tailed bacteriophages

par Joshua M. Hardy, Rhys A. Dunstan, Rhys Grinter, Matthew J. Belousoff, Jiawei Wang, Derek Pickard, Hariprasad Venugopal, Gordon Dougan, Trevor Lithgow, Fasséli Coulibaly
Publié 2020

Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time

par Astrid von Mentzer, Grace A. Blackwell, Derek Pickard, Christine J. Boinett, Enrique Joffré, Andrew J. Page, Ann-Mari Svennerholm, Gordon Dougan, Åsa Sjöling
Publié 2021

A Salmonella Typhimurium-Typhi genomic chimera: a model to study Vi polysaccharide capsule function in vivo.

par Angela M Jansen, Lindsay J Hall, Simon Clare, David Goulding, Kathryn E Holt, Andrew J Grant, Piero Mastroeni, Gordon Dougan, Robert A Kingsley
Publié 2011

Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens

par Richard T. Timms, Sam A. Menzies, Iva A. Tchasovnikarova, Lea C. Christensen, James C. Williamson, Robin Antrobus, Gordon Dougan, Lars Ellgaard, Paul J. Lehner
Publié 2016

Publisher Correction: A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

par Mailis Maes, Zoe A. Dyson, Sarah E. Smith, David A. Goulding, Catherine Ludden, Stephen Baker, Paul Kellam, Stephen T. Reece, Gordon Dougan, Josefin Bartholdson Scott
Publié 2021

Host responses to melioidosis and tuberculosis are both dominated by interferon-mediated signaling.

par Gavin C K W Koh, M Fernanda Schreiber, Ruben Bautista, Rapeephan R Maude, Susanna Dunachie, Direk Limmathurotsakul, Nicholas P J Day, Gordon Dougan, Sharon J Peacock
Publié 2013

Emergence of a New Epidemic <named-content content-type="genus-species">Neisseria meningitidis</named-content> Serogroup A Clone in the African Meningitis Belt: High-Resolution Pic...

par Araceli Lamelas, Simon R. Harris, Katharina Röltgen, Jean-Pierre Dangy, Julia Hauser, Robert A. Kingsley, Thomas R. Connor, Ali Sie, Abraham Hodgson, Gordon Dougan, Julian Parkhill, Stephen D. Bentley, Gerd Pluschke
Publié 2014

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating <italic toggle="yes">Salmonella</italic> Infection

par Amy T. Y. Yeung, Yoon Ha Choi, Amy H. Y. Lee, Christine Hale, Hannes Ponstingl, Derek Pickard, David Goulding, Mark Thomas, Erin Gill, Jong Kyoung Kim, Allan Bradley, Robert E. W. Hancock, Gordon Dougan
Publié 2019

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

par Robert C. Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja
Publié 2021

Multilocus sequence typing as a replacement for serotyping in Salmonella enterica.

par Mark Achtman, John Wain, François-Xavier Weill, Satheesh Nair, Zhemin Zhou, Vartul Sangal, Mary G Krauland, James L Hale, Heather Harbottle, Alexandra Uesbeck, Gordon Dougan, Lee H Harrison, Sylvain Brisse, S. Enterica MLST Study Group
Publié 2012

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

par Vanessa K. Wong, Stephen Baker, Thomas R. Connor, Derek Pickard, Andrew J. Page, Jayshree Dave, Niamh Murphy, Richard Holliman, Armine Sefton, Michael Millar, Zoe A. Dyson, Gordon Dougan, Kathryn E. Holt, International Typhoid Consortium
Publié 2016

Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis

par Amy T. Y. Yeung, Christine Hale, Amy H. Lee, Erin E. Gill, Wendy Bushell, David Parry-Smith, David Goulding, Derek Pickard, Theodoros Roumeliotis, Jyoti Choudhary, Nick Thomson, William C. Skarnes, Gordon Dougan, Robert E. W. Hancock
Publié 2017

Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya

par Samuel Kariuki, Zoe A Dyson, Cecilia Mbae, Ronald Ngetich, Susan M Kavai, Celestine Wairimu, Stephen Anyona, Naomi Gitau, Robert Sanaya Onsare, Beatrice Ongandi, Sebastian Duchene, Mohamed Ali, John David Clemens, Kathryn E Holt, Gordon Dougan
Publié 2021

Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae

par Matthew J. Dorman, Daryl Domman, Tomás Poklepovich, Charlotte Tolley, Gisella Zolezzi, Leanne Kane, María Rosa Viñas, Marcela Panagópulo, Miriam Moroni, Norma Binsztein, María Inés Caffer, Simon Clare, Gordon Dougan, George P. C. Salmond, Julian Parkhill, Josefina Campos, Nicholas R. Thomson
Publié 2020

Emergence of an Extensively Drug-Resistant <italic toggle="yes">Salmonella enterica</italic> Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinol...

par Elizabeth J. Klemm, Sadia Shakoor, Andrew J. Page, Farah Naz Qamar, Kim Judge, Dania K. Saeed, Vanessa K. Wong, Timothy J. Dallman, Satheesh Nair, Stephen Baker, Ghazala Shaheen, Shahida Qureshi, Mohammad Tahir Yousafzai, Muhammad Khalid Saleem, Zahra Hasan, Gordon Dougan, Rumina Hasan
Publié 2018

Genome and Transcriptome Adaptation Accompanying Emergence of the Definitive Type 2 Host-Restricted <named-content content-type="genus-species">Salmonella enterica</named-content>...

par Robert A. Kingsley, Sally Kay, Thomas Connor, Lars Barquist, Leanne Sait, Kathryn E. Holt, Karthi Sivaraman, Thomas Wileman, David Goulding, Simon Clare, Christine Hale, Aswin Seshasayee, Simon Harris, Nicholas R. Thomson, Paul Gardner, Wolfgang Rabsch, Paul Wigley, Tom Humphrey, Julian Parkhill, Gordon Dougan
Publié 2013