Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza

par Hanjun Zhao, Kelvin K. W. To, Hin Chu, Qiulu Ding, Xiaoyu Zhao, Cun Li, Huiping Shuai, Shuofeng Yuan, Jie Zhou, Kin-Hang Kok, Shibo Jiang, Kwok-Yung Yuen
Publié 2018

Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein

par Xiaohui Wang, Joy-Yan Lam, Wan-Man Wong, Chun-Kit Yuen, Jian-Piao Cai, Shannon Wing-Ngor Au, Jasper Fuk-Woo Chan, Kelvin K. W. To, Kin-Hang Kok, Kwok-Yung Yuen
Publié 2020

Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection

par Xiaohui Wang, Xiang Lin, Zihan Zheng, Bingtai Lu, Jun Wang, Andy Hee-Meng Tan, Meng Zhao, Jia Tong Loh, Sze Wai Ng, Qian Chen, Fan Xiao, Enyu Huang, King-Hung Ko, Zhong Huang, Jingyi Li, Kin-Hang Kok, Gen Lu, Xiaohui Liu, Kong-Peng Lam, Wanli Liu, Yuxia Zhang, Kwok-Yung Yuen, Tak Wah Mak, Liwei Lu
Publié 2021

Isolation of MERS-related coronavirus from lesser bamboo bats that uses DPP4 and infects human-DPP4-transgenic mice

par Susanna K. P. Lau, Rachel Y. Y. Fan, Longchao Zhu, Kenneth S. M. Li, Antonio C. P. Wong, Hayes K. H. Luk, Emily Y. M. Wong, Carol S. F. Lam, George C. S. Lo, Joshua Fung, Zirong He, Felix C. H. Fok, Rex K. H. Au-Yeung, Libiao Zhang, Kin-Hang Kok, Kwok-Yung Yuen, Patrick C. Y. Woo
Publié 2021

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

par Shuofeng Yuan, Hin Chu, Jasper Fuk-Woo Chan, Zi-Wei Ye, Lei Wen, Bingpeng Yan, Pok-Man Lai, Kah-Meng Tee, Jingjing Huang, Dongdong Chen, Cun Li, Xiaoyu Zhao, Dong Yang, Man Chun Chiu, Cyril Yip, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kong-Hung Sze, Jie Zhou, Ivy Hau-Yee Chan, Kin-Hang Kok, Kelvin Kai-Wang To, Richard Yi-Tsun Kao, Johnson Yiu-Nam Lau, Dong-Yan Jin, Stanley Perlman, Kwok-Yung Yuen
Publié 2019

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

par Hin Chu, Bingjie Hu, Xiner Huang, Yue Chai, Dongyan Zhou, Yixin Wang, Huiping Shuai, Dong Yang, Yuxin Hou, Xi Zhang, Terrence Tsz-Tai Yuen, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivy Hau-Yee Chan, Ko-Yung Sit, Dominic Chi-Chung Foo, Ian Yu-Hong Wong, Ada Tsui-Lin Ng, Tan To Cheung, Simon Ying-Kit Law, Wing-Kuk Au, Melinda A. Brindley, Zhiwei Chen, Kin-Hang Kok, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Publié 2021