Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.

Foxp3(+) regulatory T cells (Treg) play a crucial role in regulating immune tolerance. The use of Treg to restore immune tolerance is considered an attractive novel approach to inhibit autoimmune disease, including type 1 diabetes (T1D), and to prevent rejection of organ transplants. In view of the...

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Autores principales: Weiting Du, Yueh-Wei Shen, Wen-Hui Lee, Ding Wang, Sachiko Paz, Fouad Kandeel, Chih-Pin Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/4f633fe72c4746a9a6fff70f4b0d8717
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