Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.
Foxp3(+) regulatory T cells (Treg) play a crucial role in regulating immune tolerance. The use of Treg to restore immune tolerance is considered an attractive novel approach to inhibit autoimmune disease, including type 1 diabetes (T1D), and to prevent rejection of organ transplants. In view of the...
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Autores principales: | Weiting Du, Yueh-Wei Shen, Wen-Hui Lee, Ding Wang, Sachiko Paz, Fouad Kandeel, Chih-Pin Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/4f633fe72c4746a9a6fff70f4b0d8717 |
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