Structure and stability of the designer protein WRAP-T and its permutants

Abstract $$\beta $$ β -Propeller proteins are common natural disc-like pseudo-symmetric proteins that contain multiple repeats (‘blades’) each consisting of a 4-stranded anti-parallel $$\beta $$ β -sheet. So far, 4- to 12-bladed $$\beta $$ β -propellers have been discovered in nature showing large f...

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Autores principales: Bram Mylemans, Xiao Yin Lee, Ina Laier, Christine Helsen, Arnout R. D. Voet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4f79e968ad0342daa7075fc81ab3f3d7
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