Angiotensin II upregulates endothelial lipase expression via the NF-kappa B and MAPK signaling pathways.

Angiotensin II upregulates endothelial lipase expression via the NF-kappa B and MAPK signaling pathways.

<h4>Background</h4>Angiotensin II (AngII) participates in endothelial damage and inflammation, and accelerates atherosclerosis. Endothelial lipase (EL) is involved in the metabolism and clearance of high density lipoproteins (HDL), the serum levels of which correlate negatively with the...

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Main Authors: Xiaoli Zhang, Minghui Wu, Hong Jiang, Jing Hao, Qingli Zhang, Qing Zhu, Gaowa Saren, Yun Zhang, Xiaohui Meng, Xin Yue
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/4f8fc572e51442bb99b15b790714a616
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