Cinacalcet Targets the Neurokinin-1 Receptor and Inhibits PKCδ/ERK/P65 Signaling to Alleviate Dextran Sulfate Sodium-Induced Colitis

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Cinacalcet Targets the Neurokinin-1 Receptor and Inhibits PKCδ/ERK/P65 Signaling to Alleviate Dextran Sulfate Sodium-Induced Colitis

Objective: Inflammatory bowel disease is an immune-mediated chronic inflammatory disease of the gastrointestinal tract for which curative drugs are currently not available. This study was performed to assess the therapeutic effects of cinacalcet on dextran sulfate sodium (DSS)-induced colitis.Method...

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Auteurs principaux:	Yuehong Chen, Huan Liu, Qiuping Zhang, Yubin Luo, Liang Wu, Yutong Zhong, Zhigang Tang, Yaoyu Pu, Chenyang Lu, Geng Yin, Qibing Xie
Format:	article
Langue:	EN
Publié:	Frontiers Media S.A. 2021
Sujets:	cinacalcet inflammatory bowel disease neurokinin-1 receptor tumor necrosis factor α NF-κB Therapeutics. Pharmacology RM1-950
Accès en ligne:	https://doaj.org/article/4f9a4e7768d74152aecc4523183a077c
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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