Crowding alone cannot account for cosolute effect on amyloid aggregation.

Amyloid fiber formation is a specific form of protein aggregation, often resulting from the misfolding of native proteins. Aimed at modeling the crowded environment of the cell, recent experiments showed a reduction in fibrillation halftimes for amyloid-forming peptides in the presence of cosolutes...

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Autores principales: Shahar Sukenik, Regina Politi, Lior Ziserman, Dganit Danino, Assaf Friedler, Daniel Harries
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/4f9c13fda75d43e19e63758bf37c779f
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