Crowding alone cannot account for cosolute effect on amyloid aggregation.
Amyloid fiber formation is a specific form of protein aggregation, often resulting from the misfolding of native proteins. Aimed at modeling the crowded environment of the cell, recent experiments showed a reduction in fibrillation halftimes for amyloid-forming peptides in the presence of cosolutes...
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Main Authors: | Shahar Sukenik, Regina Politi, Lior Ziserman, Dganit Danino, Assaf Friedler, Daniel Harries |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/4f9c13fda75d43e19e63758bf37c779f |
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