Exploring the sequence features determining amyloidosis in human antibody light chains

Abstract The light chain (AL) amyloidosis is caused by the aggregation of light chain of antibodies into amyloid fibrils. There are plenty of computational resources available for the prediction of short aggregation-prone regions within proteins. However, it is still a challenging task to predict th...

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Autores principales: Puneet Rawat, R. Prabakaran, Sandeep Kumar, M. Michael Gromiha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4fa62a20ac6040f6894d6f47565edcc3
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