Exploring the sequence features determining amyloidosis in human antibody light chains

Abstract The light chain (AL) amyloidosis is caused by the aggregation of light chain of antibodies into amyloid fibrils. There are plenty of computational resources available for the prediction of short aggregation-prone regions within proteins. However, it is still a challenging task to predict th...

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Bibliographic Details
Main Authors: Puneet Rawat, R. Prabakaran, Sandeep Kumar, M. Michael Gromiha
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/4fa62a20ac6040f6894d6f47565edcc3
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