Deep generative neural network for accurate drug response imputation

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Deep generative neural network for accurate drug response imputation

Drug response in cancer patients vary dramatically due to inter- and intra-tumor heterogeneity and transcriptome context plays a significant role in shaping the actual treatment outcome. Here, the authors develop a deep variational autoencoder model to compress gene signatures into latent vectors an...

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Bibliographic Details
Main Authors:	Peilin Jia, Ruifeng Hu, Guangsheng Pei, Yulin Dai, Yin-Ying Wang, Zhongming Zhao
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/4fb77b5018df4b45a1a0baa6a40058e4
Tags:	Add Tag No Tags, Be the first to tag this record!

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