Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function.
Vacuolar-type H(+)-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a...
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Main Authors: | An Qin, Tak S Cheng, Zhen Lin, Nathan J Pavlos, Qing Jiang, Jiake Xu, Ke R Dai, Ming H Zheng |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/4fc5ed48e81d4d05a1e72eb3d2e29293 |
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