Evidence that transcription factor AP-2γ is not required for Oct4 repression in mouse blastocysts.

In mouse blastocysts segregation of the inner cell mass (ICM) and the trophectoderm (TE) is regulated by the mutually antagonistic effects of the transcription factors Oct4 and Cdx2 expressed in the ICM and TE, respectively. In contrast, in other species such as bovine and human, Oct4 is not restric...

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Auteurs principaux: Inchul Choi, Timothy S Carey, Catherine A Wilson, Jason G Knott
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
Q
Accès en ligne:https://doaj.org/article/50084a6426c54733a7afe91e10ae6224
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