Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation.
One characteristic of tumor microenvironment is oxygen fluctuation, which results from hyper-proliferation and abnormal metabolism of tumor cells as well as disorganized neo-vasculature. Reoxygenation of tumors can induce oxidative stress, which leads to DNA damage and genomic instability. Although...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Acceso en línea: | https://doaj.org/article/5051598b334d409e998b0c9d7bce035c |
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