A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.

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Autores principales: Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/5054f4fdda3244658206c728b04b321a
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https://doaj.org/article/5054f4fdda3244658206c728b04b321a

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