A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.

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Autores principales: Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5054f4fdda3244658206c728b04b321a
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spelling oai:doaj.org-article:5054f4fdda3244658206c728b04b321a2021-12-02T15:34:22ZA variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes10.1038/s41467-018-06235-92041-1723https://doaj.org/article/5054f4fdda3244658206c728b04b321a2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06235-9https://doaj.org/toc/2041-1723Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.Tianyi ZhangGuifeng WeiChristopher J. MillardRoman FischerRebecca KonietznyBenedikt M. KesslerJohn W. R. SchwabeNeil BrockdorffNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tianyi Zhang
Guifeng Wei
Christopher J. Millard
Roman Fischer
Rebecca Konietzny
Benedikt M. Kessler
John W. R. Schwabe
Neil Brockdorff
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
description Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.
format article
author Tianyi Zhang
Guifeng Wei
Christopher J. Millard
Roman Fischer
Rebecca Konietzny
Benedikt M. Kessler
John W. R. Schwabe
Neil Brockdorff
author_facet Tianyi Zhang
Guifeng Wei
Christopher J. Millard
Roman Fischer
Rebecca Konietzny
Benedikt M. Kessler
John W. R. Schwabe
Neil Brockdorff
author_sort Tianyi Zhang
title A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
title_short A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
title_full A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
title_fullStr A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
title_full_unstemmed A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
title_sort variant nurd complex containing pwwp2a/b excludes mbd2/3 to regulate transcription at active genes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5054f4fdda3244658206c728b04b321a
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