The recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters

Abstract The anti-inflammatory effects of the plant protease inhibitor BbCI (Bauhinia bauhinioides cruzipain inhibitor), which blocks elastase, cathepsin G, and L, and proteinase 3 has been demonstrated. Here, we investigated the recombinant rBbCI-His(6) (containing a histidine tail) in an experimen...

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Autores principales: Cleide Oliveira, Mayara Vioto Valois, Tatiana Fontes Ottaiano, Antonio Miranda, Daiane Hansen, Misako Uemura Sampaio, Maria Luiza Vilela Oliva, Francisco Humberto de Abreu Maffei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5077b7d1b41043ba8742f50087c68a8f
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