Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability

The interplay between driver mutations and aneuploidy during tumorigenesis is largely unexplored. Here, the authors show two types of associations, leading to different therapeutic vulnerabilities and prognoses.

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Autores principales: Noam Auslander, Yuri I. Wolf, Eugene V. Koonin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
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Acceso en línea:https://doaj.org/article/508a4ed569754b8f9b56fc8d430a3718
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