Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification
Plant cells maintain strict proton gradients over different membranes. Here, Dejonghe et al. show that several protonophores, including the known tyrosine kinase inhibitor TyrphostinA23, inhibit clathrin-mediated endocytosis by disturbing these gradients and causing cytoplasmic acidification.
Enregistré dans:
Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/50a7efdd53054d58bdc66c48775ef3ba |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|