Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

Abstract Annexin A5 (AnxA5) is known to have anti-inflammatory and anti-apoptotic properties. Inflammation and apoptosis are key processes in post-ischemic cardiac remodeling. In this study, we investigated the effect of AnxA5 on left ventricular (LV) function and remodeling three weeks after myocar...

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Bibliographic Details
Main Authors: Rob C. M. de Jong, Niek J. Pluijmert, Margreet R. de Vries, Knut Pettersson, Douwe E. Atsma, J. Wouter Jukema, Paul H. A. Quax
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/50bd8d889bfd42e0baca7bd420a4b082
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