MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade

Abstract Tumour-promoting inflammation is a hallmark of cancer, and chronic inflammatory disease increases the risk of cancer. In this context, MYD88, a downstream signalling molecule of Toll-like receptors that initiates inflammatory signalling cascades, has a critical role in tumour development in...

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Autores principales: Atsuko Tanimura, Akane Nakazato, Nobuyuki Tanaka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/511c17c2004944a2abab9d4c0af364f7
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