Structural and Computational Study of the GroEL–Prion Protein Complex
The molecular chaperone GroEL is designed to promote protein folding and prevent aggregation. However, the interaction between GroEL and the prion protein, PrP<sup>C</sup>, could lead to pathogenic transformation of the latter to the aggregation-prone PrP<sup>Sc</sup> form. H...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/512228c76fd84cecb55b734f86e49b80 |
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