Structural and Computational Study of the GroEL–Prion Protein Complex

The molecular chaperone GroEL is designed to promote protein folding and prevent aggregation. However, the interaction between GroEL and the prion protein, PrP<sup>C</sup>, could lead to pathogenic transformation of the latter to the aggregation-prone PrP<sup>Sc</sup> form. H...

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Auteurs principaux: Aleksandra A. Mamchur, Andrei V. Moiseenko, Irina S. Panina, Igor A. Yaroshevich, Sofia S. Kudryavtseva, Evgeny B. Pichkur, Olga S. Sokolova, Vladimir I. Muronetz, Tatiana B. Stanishneva-Konovalova
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/512228c76fd84cecb55b734f86e49b80
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