MicroRNA-146a limits tumorigenic inflammation in colorectal cancer

MicroRNA-146a limits tumorigenic inflammation in colorectal cancer

Activation of interleukin-17 (IL-17) receptor signaling within intestinal epithelial cells (IECs) promotes colorectal cancer development. Here, the authors show that miR-146a limits inflammation-induced colorectal carcinogenesis by inhibiting both IL-17 induction from myeloid cells and inhibiting IL...

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Autores principales: Lucien P. Garo, Amrendra K. Ajay, Mai Fujiwara, Galina Gabriely, Radhika Raheja, Chantal Kuhn, Brendan Kenyon, Nathaniel Skillin, Ryoko Kadowaki-Saga, Shrishti Saxena, Gopal Murugaiyan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/51279124a70d4a388df327b36573d6f3
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https://doaj.org/article/51279124a70d4a388df327b36573d6f3

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