Multistage hematopoietic stem cell regulation in the mouse: A combined biological and mathematical approach
Summary: We have reconciled steady-state and stress hematopoiesis in a single mathematical model based on murine in vivo experiments and with a focus on hematopoietic stem and progenitor cells. A phenylhydrazine stress was first applied to mice. A reduced cell number in each progenitor compartment w...
Guardado en:
Autores principales: | Céline Bonnet, Panhong Gou, Simon Girel, Vincent Bansaye, Catherine Lacout, Karine Bailly, Marie-Hélène Schlagetter, Evelyne Lauret, Sylvie Méléard, Stéphane Giraudier |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/51509df1070a4d4585faa5eea2a5d7f2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Constraint-based modeling of yeast mitochondria reveals the dynamics of protein import and iron-sulfur cluster biogenesis
por: Carl Malina, et al.
Publicado: (2021) -
Infecting human hematopoietic stem and progenitor cells with SARS-CoV-2
por: Hector Huerga Encabo, et al.
Publicado: (2021) -
Principles underlying the complex dynamics of temperature entrainment by a circadian clock
por: Philipp Burt, et al.
Publicado: (2021) -
Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle
por: Bronson R. Weston, et al.
Publicado: (2021) -
Neuronal population models reveal specific linear conductance controllers sufficient to rescue preclinical disease phenotypes
por: Sushmita L. Allam, et al.
Publicado: (2021)