Multiple E3s promote the degradation of histone H3 variant Cse4

Abstract The histone H3-like protein Cse4/CENP-A acts as a key molecular marker that differentiates the special centromeric chromatin structures from bulk nucleosomes. As altered Cse4/CENP-A activity leads to genome instability, it is pivotal to understand the mechanism underlying Cse4 regulation. H...

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Autores principales: Haili Cheng, Xin Bao, Xin Gan, Shiwen Luo, Hai Rao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/51778c3d13ec488b907e80f30c51fb76
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