IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model
Mesenchymal stem cells (MSCs) are used in various studies to induce immunomodulatory effects in clinical conditions associated with immune dysregulation such as graft versus host disease (GvHD). However, most of these clinical trials failed to go beyond early phase 2 studies because of limited effic...
Enregistré dans:
Auteurs principaux: | Cuiping Zhang, Mina Delawary, Peng Huang, Jennifer A. Korchak, Koji Suda, Abba C. Zubair |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/51a8916a21044af2ac4c6c0f1c2489c4 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Immunometabolic Therapeutic Targets of Graft-versus-Host Disease (GvHD)
par: Kudakwashe Mhandire, et autres
Publié: (2021) -
IMMUNOBIOLOGY OF ACUTE GRAFT-VERSUS-HOST DISEASE
par: G. A. Efimov, et autres
Publié: (2016) -
Human Amniotic Mesenchymal Stem Cells Inhibit aGVHD by Regulating Balance of Treg and T Effector Cells
par: Gao Y, et autres
Publié: (2021) -
Donor‐derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation
par: Ryo Hanaki, et autres
Publié: (2021) -
LYMPHOPENIA AS A FACTOR INVOLVED IN THE AUTOIMMUNITY DEVELOPMENT IN MURINE GRAFT VS. HOST DISEASE
par: E. V. Goiman, et autres
Publié: (2012)