Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins

The Ups/PRELI family mediates intramitochondrial lipid distribution and synthesis by shuttling phospholipids between both mitochondrial membranes. Here the authors combine X-ray crystallography, MD simulations and yeast genetic screens and identify residues that are important for Ups/PRELI lipid spe...

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Autores principales: Xeni Miliara, Takashi Tatsuta, Jamie-Lee Berry, Sarah L. Rouse, Kübra Solak, Dror S. Chorev, Di Wu, Carol V. Robinson, Stephen Matthews, Thomas Langer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/51be78de046c436f8df261a65888f530
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