N-Demethylsinomenine, an active metabolite of sinomenine, attenuates chronic neuropathic and inflammatory pain in mice

Abstract Chronic pain is a significant public health problem that afflicts nearly 30% of the global population, but current pharmacotherapies are insufficient. Previous report indicated that N-demethylsinomenine, an active metabolite of sinomenine, is efficacious against postoperative pain. The pres...

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Autores principales: Zhiyong Zhou, Nanqing Qiu, Yuntao Ou, Qianqian Wei, Wenting Tang, Mingcong Zheng, Yaluan Xing, Jie-Jia Li, Yong Ling, Junxu Li, Qing Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/520706d26a654c56b70421cfac4b6135
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