Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology

ABSTRACT During its lysogenic life cycle, the phage genome is integrated into the host chromosome by site-specific recombination. In this report, we analyze lambda phage integration into noncanonical sites using next-generation sequencing and show that it generates significant genetic diversity by t...

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Autores principales: Yu Tanouchi, Markus W. Covert
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/522da07a5e1d4183898daef6f10ab1f7
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