Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology
ABSTRACT During its lysogenic life cycle, the phage genome is integrated into the host chromosome by site-specific recombination. In this report, we analyze lambda phage integration into noncanonical sites using next-generation sequencing and show that it generates significant genetic diversity by t...
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2017
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Acceso en línea: | https://doaj.org/article/522da07a5e1d4183898daef6f10ab1f7 |
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