The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysis.

Calcium-dependent protein kinases (CDPKs) are conserved in plants and apicomplexan parasites. In Toxoplasma gondii, TgCDPK3 regulates parasite egress from the host cell in the presence of a calcium-ionophore. The targets and the pathways that the kinase controls, however, are not known. To identify...

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Autores principales: Moritz Treeck, John L Sanders, Rajshekhar Y Gaji, Kacie A LaFavers, Matthew A Child, Gustavo Arrizabalaga, Joshua E Elias, John C Boothroyd
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/524d9946ca3f4389accbbde822d34a7b
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