Immune Synapse Residency of Orai1 Alters Ca<sup>2+</sup> Response of T Cells

CRAC, which plays important role in Ca<sup>2+</sup>-dependent T-lymphocyte activation, is composed of the ER-resident STIM1 and the plasma membrane Orai1 pore-forming subunit. Both accumulate at the immunological synapse (IS) between a T cell and an antigen-presenting cell (APC). We hypo...

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Autores principales: Orsolya Voros, György Panyi, Péter Hajdu
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/524ec433210a453aa979554d90566f7e
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