Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.

<h4>Background</h4>Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce alpha-defensins1-3 and that alpha-defensins1-3 modulate DC generation and maturation...

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Autores principales: Marta Rodríguez-García, Núria Climent, Harold Oliva, Víctor Casanova, Rafael Franco, Agathe Leon, José M Gatell, Felipe García, Teresa Gallart
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/526a2652e57a4d728c8c794a805ccfde
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