A system-wide mislocalization of RNA-binding proteins in motor neurons is a new feature of ALS
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of motor neurons. Mislocalization of TAR DNA-binding protein 43 (TDP-43) is an early event in the formation of cytoplasmic TDP-43-positive inclusions in motor neurons and a hallmark of ALS. Howeve...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/52a7d3f8cf4a4ab29473f8dcf59123f4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|