Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology.
A large number of cellular level abnormalities have been identified in the hippocampus of schizophrenic subjects. Nonetheless, it remains uncertain how these pathologies interact at a system level to create clinical symptoms, and this has hindered the development of more effective antipsychotic medi...
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/52b38aab149b40a3bbc80148cfde341a |
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