Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology.
A large number of cellular level abnormalities have been identified in the hippocampus of schizophrenic subjects. Nonetheless, it remains uncertain how these pathologies interact at a system level to create clinical symptoms, and this has hindered the development of more effective antipsychotic medi...
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Autores principales: | Peter J Siekmeier, David P vanMaanen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/52b38aab149b40a3bbc80148cfde341a |
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