<italic toggle="yes">Cryptococcus neoformans</italic> Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model

<italic toggle="yes">Cryptococcus neoformans</italic> Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model

ABSTRACT Cryptococcus neoformans is an encapsulated fungal pathogen that causes meningoencephalitis. There are no prophylactic tools for cryptococcosis. Previously, our group showed that a C. neoformans mutant lacking the gene encoding sterylglucosidase (Δsgl1) induced protection in both immunocompe...

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Bibliographic Details
Main Authors: Ana Caroline Colombo, Antonella Rella, Tyler Normile, Luna S. Joffe, Patricia M. Tavares, Glauber R. de S. Araújo, Susana Frases, Erika P. Orner, Amir M. Farnoud, Bettina C. Fries, Brian Sheridan, Leonardo Nimrichter, Marcio L. Rodrigues, Maurizio Del Poeta
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Cryptococcus neoformans
capsule
extracellular vesicles
fungal infection
glucuronoxylomannan
glycolipids
Microbiology
QR1-502
Online Access:https://doaj.org/article/52d022ef29b64652848b6962dc1e3a60
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