Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis

Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis

ABSTRACT To visualize the personalized distributions of pathogens and chemical environments, including microbial metabolites, pharmaceuticals, and their metabolic products, within and between human lungs afflicted with cystic fibrosis (CF), we generated three-dimensional (3D) microbiome and metabolo...

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Main Authors: Alexey V. Melnik, Yoshiki Vázquez-Baeza, Alexander A. Aksenov, Embriette Hyde, Andrew C. McAvoy, Mingxun Wang, Ricardo R. da Silva, Ivan Protsyuk, Jason V. Wu, Amina Bouslimani, Yan Wei Lim, Tal Luzzatto-Knaan, William Comstock, Robert A. Quinn, Richard Wong, Greg Humphrey, Gail Ackermann, Timothy Spivey, Sharon S. Brouha, Nuno Bandeira, Grace Y. Lin, Forest Rohwer, Douglas J. Conrad, Theodore Alexandrov, Rob Knight, Pieter C. Dorrestein, Neha Garg
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
GNPS
Pseudomonas
spatial mapping
Stenotrophomonas
antibiotic distribution
cystic fibrosis
Microbiology
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Online Access:https://doaj.org/article/52f7a097d5b64c42bd3fbf8ea662a647
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https://doaj.org/article/52f7a097d5b64c42bd3fbf8ea662a647

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