Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles.

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Autores principales: Philipp Schäfer, Thomas Palacin, Mireia Sidera, Stephen P. Fletcher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5302516147a6471d9a7f5e8a78a2cbc9
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