Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles.
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/5302516147a6471d9a7f5e8a78a2cbc9 |
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| Sumario: | Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles. |
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