Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles.

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Autores principales:	Philipp Schäfer, Thomas Palacin, Mireia Sidera, Stephen P. Fletcher
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5302516147a6471d9a7f5e8a78a2cbc9
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spelling	oai:doaj.org-article:5302516147a6471d9a7f5e8a78a2cbc92021-12-02T17:06:17ZAsymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates10.1038/ncomms157622041-1723https://doaj.org/article/5302516147a6471d9a7f5e8a78a2cbc92017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15762https://doaj.org/toc/2041-1723Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles.Philipp SchäferThomas PalacinMireia SideraStephen P. FletcherNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Philipp Schäfer Thomas Palacin Mireia Sidera Stephen P. Fletcher Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
description	Asymmetric Suzuki-Miyaura procedures often have difficulty incorporating heterocyclic reagents, despite the importance of these in the pharmaceutical industry. Here the authors report a rhodium catalysed cross-coupling that tolerates a wide variety of nucleophiles including a range of heterocycles.
format	article
author	Philipp Schäfer Thomas Palacin Mireia Sidera Stephen P. Fletcher
author_facet	Philipp Schäfer Thomas Palacin Mireia Sidera Stephen P. Fletcher
author_sort	Philipp Schäfer
title	Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
title_short	Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
title_full	Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
title_fullStr	Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
title_full_unstemmed	Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
title_sort	asymmetric suzuki-miyaura coupling of heterocycles via rhodium-catalysed allylic arylation of racemates
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5302516147a6471d9a7f5e8a78a2cbc9
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Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

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