Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins.
<h4>Background</h4>Generating autologous pluripotent stem cells for therapeutic applications will require the development of efficient DNA-free reprogramming techniques. Transfecting cells with in vitro-transcribed, protein-encoding RNA is a straightforward method of directly expressing...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2010
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| Accès en ligne: | https://doaj.org/article/53032392db0b4a7fad61f832d4511802 |
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