Arylmethylene hydrazine derivatives containing 1,3-dimethylbarbituric moiety as novel urease inhibitors

Abstract A new series of arylmethylene hydrazine derivatives bearing 1,3-dimethylbarbituric moiety 7a–o were designed, synthesized, and evaluated for their in vitro urease inhibitory activity. All the title compounds displayed high anti-urease activity, with IC50 values in the range of 0.61 ± 0.06–4...

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Autores principales: Keyvan Pedrood, Homa Azizian, Mohammad Nazari Montazer, Maryam Mohammadi‐Khanaposhtani, Mohammad Sadegh Asgari, Mehdi Asadi, Saeed Bahadorikhalili, Hossein Rastegar, Bagher Larijani, Massoud Amanlou, Mohammad Mahdavi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/532fe090754145b8a11fda665c0b10b4
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