ATP-dependent hydroxylation of an unactivated primary carbon with water
Monooxygenases catalyse the hydroxylation of C-H bonds using oxygen as a co-substrate, which, in turn, is unavailable for anaerobic bacteria. Here, the authors report a three-step reaction cascade involving two hydroxylases and one dehydratase which hydroxylate the C26 methyl group of cholesterol wi...
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Autores principales: | Christian Jacoby, Sascha Ferlaino, Dominik Bezold, Henning Jessen, Michael Müller, Matthias Boll |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/535dccae5c7b42d891408b93dd8fd29d |
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