Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

Inflammatory bowel disease is caused by chronic inflammation of the gastrointestinal tract and disturbed immune responses. Here the authors present examination of Cortistatin analogues that display enhanced half-life stability whilst maintaining immunomodulatory functionality.

Saved in:
Bibliographic Details
Main Authors: Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Eric Aragón, Xavier Verdaguer, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Eduard Puig, Jimena Fernández-Carneado, Berta Ponsati, Mario Delgado, Antoni Riera, Maria J. Macias
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/538094955b874388ace1e053acd30f22
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/538094955b874388ace1e053acd30f22

Similar Items