A Multifunctional Polymeric Micelle for Targeted Delivery of Paclitaxel by the Inhibition of the P-Glycoprotein Transporters

P-glycoprotein (P-gP) efflux-mediated multidrug resistance is a fundamental aspect of chemotherapeutic failure in oncology. The current study aims to deliver paclitaxel (PTX) specifically at the target site with improved in vivo efficacy of poorly permeable PTX against solid tumors. Multifunctional...

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Autores principales: Sobia Razzaq, Aisha Rauf, Abida Raza, Sohail Akhtar, Tanveer A. Tabish, Mansur Abdullah Sandhu, Muhammad Zaman, Ibrahim M. Ibrahim, Gul Shahnaz, Abbas Rahdar, Ana M. Díez-Pascual
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/5392668d811a4f03bcf1fa7882ced679
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